COMPLEMENT C5A INDUCES THE GENERATION OF NEUTROPHIL EXTRACELLULAR TRAPS BY INHIBITING MITOCHONDRIAL STAT3 TO PROMOTE THE DEVELOPMENT OF ARTERIAL THROMBOSIS

Complement C5a induces the generation of neutrophil extracellular traps by inhibiting mitochondrial STAT3 to promote the development of arterial thrombosis

Abstract Background Thrombotic events cannot be completely prevented by antithrombotics, implicating a therapeutic gap due to inflammation, a not yet sufficiently addressed mechanism.Neutrophil extracellular traps (NETs) are an essential interface between inflammation and thrombosis, but exactly how the NETotic process is initiated and maintained d

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Determination of the relatedness, ease of hybridization and gene exchange among members of the genus Capsicum in Nigeria

activecare spitfire The fruit of Capsicum plants have a variety of names depending on place and type.This research was focused at studying the exchange of genes amongst members of the genus Capsicum in Nigeria.The process of interspecific and intervarietal hybridization of two (2) species of the genus Capsicum; C.annuum and C.frutasense were carrie

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A Cross-Sectional Study to Understand Socio Demographic Profile of Couples Who Adopted Permanent Sterilization in Urban Slums of Surat City

Introduction: There is big gap in the adoption of male and female sterilization.It is necessary to understand socio demographic factors of couples who adopted permanent sterilization.Aims & Objectives: The study was done with the aim to document the socio demographic profile of couples who adopted permanent sterilization in urban slums of Surat cit

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Physiologically Guided Thrombolysis in Pulmonary Embolism

We describe the case of a 69-year-old woman who 2334-080 presented with submassive pulmonary embolism without overt shock, but with significant signs of right ventricular failure and dyspnea on minimal exertion.She was managed using a point-of-care ultrasound and pulmonary artery pressure-guided delta zeta jersey approach in order to minimize total

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